Developments of 2040's

Mind uploading becomes possible. Nanomachines could be directly inserted into the brain and could interact with brain cells to totally control incoming and outgoing signals. As a result, truly full-immersion virtual reality could be generated without the need for any external equipment. Afferent nerve pathways could be blocked, totally canceling out the "real" world and leaving the user with only the desired virtual experience.

• Brain nanobots could also elicit emotional responses from users.
• Using brain nanobots, recorded or real-time brain transmissions of a person's daily life known as "experience beamers" will be available for other people to remotely experience. This is very similar to how the characters in Being John Malkovich were able to enter the mind of Malkovich and see the world through his eyes.
• Recreational uses aside, nanomachines in peoples' brains will allow them to greatly expand their cognitive, memory and sensory capabilities, to directly interface with computers, and to "telepathically" communicate with other, similarly augmented humans via wireless networks.
• The same nanotechnology should also allow people to alter the neural connections within their brains, changing the underlying basis for the person's intelligence, memories and personality.
• Human body 2.0 (as Kurzweil calls it) is incrementally accumulated into this decade. It consists of a nanotechnological system of nourishment and circulation, obsolescing many internal organs, and an improved skeleton.
• Human body 3.0 is gradually implemented during this decade. It lacks a fixed, corporeal form and can alter its shape and external appearance at will via foglet-like nanotechnology.
• People spend most of their time in full-immersion virtual reality ( The Matrix as a good example of what the advanced virtual worlds will be like, without the dystopian twist).
• Foglets are in use.